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Chronic disease

In Focus

Chronic Disease

Harvardscientists are exploring faster diagnostics, better symptom management, and promising cures for conditions that have a long-term impact on our health.

Leading the way


Eliminating a global chronic infection

Carole Mitnick

As a professor of global health and social medicine at HarvardMedical School and the research director of endTB, Carole has played a crucial role in creating new tuberculosis treatment regimens, developing implementation plans, and building local know-how to try to eliminate the chronic infection globally.

Acute research for chronic conditions

A globe and a stethoscope

Reducing avoidable deaths from chronic disease leads to 鈥渟ubstantial鈥 economic savings

A Harvardstudy found that the economic value of reducing avoidable deaths from cardiovascular disease alone would be between 2 and 8% of annual income in 2019 in any region of the world.

  • Chronic heart disease

American heart health is worsening

In the U.S., progress in cardiovascular health has largely stalled out and in some ways worsened鈥攅ven as increasingly effective treatments and interventions come to market.

Doctor Rishi Wadhera
  • Chronic pain

The connection between sleep and pain

A newly identified chemical link between chronic pain and sleep loss could inform new treatments.

A person with back pain
  • Chronic Lung Disease

Vaping can lead to restricted airways and scarred lung tissue

A Harvardteam found damage in the small airways of vapers, similar to the lung damage typically seen in soldiers who had inhaled mustard gas.

A man vaping
  • Chronic inflammation

Working out activates inflammation-fighting T cells

A Harvardstudy demonstrated that the immune system exerts powerful effects inside the muscle during exercise.

The legs of runners in a race

A body of research

an illustration of kidneys

A newly launched startup is building upon innovations developed at Harvardto engineer functional kidney tissue for renal repair and replacement therapy.

HarvardProfessor Doug Melton and his team are testing a new treatment that could make insulin shots obsolete.

an illustration of a heart

Harvardresearch, which offers clues for treatment and prevention of aortic aneurysms, may also address hypertension, which affects nearly half of all adults in the U.S.

Harvardresearch found for the first time common genetic factors shared between obesity and certain types of asthma.

an illustration of a brain

CTE is not just caused by repeated head impact but is also linked to DNA damage similar to that seen in Alzheimer鈥檚 disease.

Harvardresearchers developed a way to objectively measure tinnitus, which may help in developing future therapies.

an illustration of a liver

Harvardresearchers have found an increased risk of liver cancer and chronic liver disease mortality among women who consume sugar-sweetened beverages on a daily basis.

Harvardexperts are finding novel ways to identify people at high risk of developing clinical Parkinson鈥檚 disease later in life.

an illustration of a uterus

A team at Harvardidentified an unexpected avenue toward alleviating the symptoms of endometriosis, which has proven difficult to treat effectively.

Good habits for prevention

A healthy diet

A Harvardstudy shows that eating a , whole grains, and unsaturated fats throughout midlife may increase an individual鈥檚 odds of living to at least 70 years old, .

Moderate exercise

Harvardresearch showed that , increases one鈥檚 odds of reaching 70 free of mental health issues, physical impairments, memory issues, and chronic disease.

Less drinking, no smoking

Harvardresearch, including the , has illuminated that reducing or eliminating alcohol and abstaining from smoking can increase years lived .